山西五台人，中共党员，博士，硕士生导师。研究方向：功能食品开发、分子动力学模拟。科研项目 1. 山西省自然科学基金，黄芩素/黄芩苷抑制PD-1/PD-L1相互作用的分子动力学模拟和体外活性研究，2023.01-2025.12，在研，主持。 2. 山西师范大学自然科学基金，多酚抑制PD-1/PD-L1通路的分子机制研究，山西师范大学自然科学基金，2024.11-2026.11，在研，主持。 发表论文 1. Yan Guo, Jinchang Tong, Yilin Guo, Xinyue Song, Kaixin Shi, Zichao Guo, Boping Liu*, Jianguo Xu*, Interaction, stability and bioaccessibility of bovine serum albumin-quercetin/myricetin complexes: Multi-spectroscopy and molecular dynamics simulation studies, Food Hydrocolloids, 2025, 110836. 2. Yan Guo, Jianhuai Liang, Boping Liu*, Yulong Jin*, Molecular Mechanism of Food-Derived Polyphenols on PD-L1 Dimerization: A Molecular Dynamics Simulation Study, International Journal of Molecular Sciences, 2021, 20. 3. Yan Guo, Yulong Jin*, Bingfeng Wang, Boping Liu*, Molecular Mechanism of Small-Molecule Inhibitors in Blocking the PD-1/PD-L1 Pathway through PD-L1 Dimerization, International Journal of Molecular Sciences, 2021, 9. 4. Yan Guo, Jinchang Tong, Jianhuai Liang, Kaixin Shi, Xinyue Song, Zichao Guo, Boping Liu*, Jianguo Xu*, Molecular insight into binding affinities and blockade effects of selected flavonoid compounds on the PD-1/PD-L1 pathway, RSC Advances, 2024, 14.

功能食品开发、分子动力学模拟

山西五台人，中共党员，博士，硕士生导师。研究方向：功能食品开发、分子动力学模拟。科研项目 1. 山西省自然科学基金，黄芩素/黄芩苷抑制PD-1/PD-L1相互作用的分子动力学模拟和体外活性研究，2023.01-2025.12，在研，主持。 2. 山西师范大学自然科学基金，多酚抑制PD-1/PD-L1通路的分子机制研究，山西师范大学自然科学基金，2024.11-2026.11，在研，主持。 发表论文 1. Yan Guo, Jinchang Tong, Yilin Guo, Xinyue Song, Kaixin Shi, Zichao Guo, Boping Liu*, Jianguo Xu*, Interaction, stability and bioaccessibility of bovine serum albumin-quercetin/myricetin complexes: Multi-spectroscopy and molecular dynamics simulation studies, Food Hydrocolloids, 2025, 110836. 2. Yan Guo, Jianhuai Liang, Boping Liu*, Yulong Jin*, Molecular Mechanism of Food-Derived Polyphenols on PD-L1 Dimerization: A Molecular Dynamics Simulation Study, International Journal of Molecular Sciences, 2021, 20. 3. Yan Guo, Yulong Jin*, Bingfeng Wang, Boping Liu*, Molecular Mechanism of Small-Molecule Inhibitors in Blocking the PD-1/PD-L1 Pathway through PD-L1 Dimerization, International Journal of Molecular Sciences, 2021, 9. 4. Yan Guo, Jinchang Tong, Jianhuai Liang, Kaixin Shi, Xinyue Song, Zichao Guo, Boping Liu*, Jianguo Xu*, Molecular insight into binding affinities and blockade effects of selected flavonoid compounds on the PD-1/PD-L1 pathway, RSC Advances, 2024, 14.

功能食品开发、分子动力学模拟